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Oxygen Instability in Hyperoxemia Blood Gas Samples and the Role of Analysis Timing
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Malihe Salimi-Bani , Amir Vahedian-Azimi *  |
| Nursing Care Research Center, Clinical Sciences Institute, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran |
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Abstract: (16 Views) |
Letter to Editorial
Measurement of the partial pressure of oxygen (pO₂) is central to the assessment of oxygenation in critically ill patients, and many clinical decisions, such as adjustment of the fraction of inspired oxygen (FiO₂) and calculation of the PaO₂/FiO₂ ratio, rely on it. However, pO₂ is one of the least stable blood gas parameters, because oxygen moves continuously between the blood and the surrounding air until equilibrium is reached. This instability is more important in arterial samples with high oxygen levels (hyperoxemia), in which the oxygen tension is far above that of room air and delay in analysis can cause a falsely low and substantial reduction in the measured value. |
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Full-Text [PDF 1115 kb]
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Type of Study: Research |
Subject:
Special Received: 2026/01/3 | Accepted: 2026/01/3 | Published: 2026/01/5
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